|
|
|
© Dirk Biddle
i) Blood Urea Nitrogen (BUN) is a waste product produced in the liver and eliminated through the kidneys. BUN levels are interpreted in conjunction with creatinine levels to monitor kidney function. High values may mean that the kidneys are not working as well as they should. BUN levels also may be elevated because of dehydration or blood in the gastrointestinal tract. BUN is also affected by high protein diets and/or strenuous exercise which raise levels, and by liver disease, pregnancy or malnutrition which lower them.
ii) Creatinine is a compound that is made primarily in the liver and transported to the muscles where it is used as an energy source for muscle activity. Creatinine is produced in your muscles when a compound called creatine spontaneously breaks down. The kidneys excrete creatinine, so blood levels are a good measure of how well the kidneys are functioning. High values, especially with high BUN levels, may indicate problems with the kidneys.
iii) Uric Acid is normally excreted in urine. High values are associated with gout (Uric acid forms into crystals that are then deposited in the joints and other tissues), arthritis, kidney problems and the use of some diuretics.